Autoria: SILVA, M. V. G. B.; OLIVEIRA JUNIOR, G.; REY, F. S. B.; GIACHETTO, P. F.; MACHADO, M. A.; VERNEQUE, R. da S.; FERRAZ, J. B. S.

Resumo: The aim of this work was to investigate, based on a high density BovineHD SNP array, the abundance and distributions of CNVs and CNVR in a Gyr cattle population from Brazil. Genotype data of representative bulls were recorded, totaling 476 Gyr animals. For CNV identification was used the PennCNV software and the CNVRs were determined by the CNVRuler software. A total of 26,672 CNVs were found, beingon average 62 CNV per animal. Also, 1,898 CNVRs were detected on the autosomal chromosomes. Also, 1,898 CNVRs were detected on the autosomal chromosomes with 96% of these between 1.1 Kb to 100 Kb. The Ensembl's VEP tool, using the CNVRs information as input, found 913 coding regions, suggesting that exon regions were duplicated. In summary, the results help to better understand the Gyr genome and suggest that CNVRs might have some relationship with production traits.

Ano de publicação: 2014

Tipo de publicação: Artigo em anais e proceedings

Unidade: Embrapa Gado de Leite

Palavras-chave: Bos Indicus, Bovino, Cattle, Dairy cattle, Gado Zebu, Gado de corte, Genomics, Polimorfismo de nucleotídeo único, Single nucleotide polymorphism