POTION: an end-to-end pipeline for positive Darwinian selection detection in genome-scale data through phylogenetic comparison of protein-coding genes.

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Author(s): HONGO, J. A.; CASTRO, G. de; CINTRA, L.; ZERLOTINI, A.; LOBO, F.

Summary: We present POTION, an open source, modular and end-to-end software for genome-scale detection of positive Darwinian selection in groups of homologous coding sequences. Our software represents a key step towards genome-scale, automated detection of positive selection, from predicted coding sequences and their homology relationships to high-quality groups of positively selected genes.

Publication year: 2015

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