A single dose of purple grape juice improves physical performance and antioxidant activity in runners: a randomized, crossover, double-blind, placebo study.

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Author(s): TOSCANO, L. de L. T.; SILVA, A. S.; FRANÇA, A. C. L. de; SOUSA, B. R. V. de; ALMEIDA FILHO, E. J. B. de; COSTA, M. da S.; BIASOTO, A. C. T.; SILVA, D. F. da; SENA, K. de F.; CERQUEIRA, G. S.; GONÇALVES, M. da C. R.

Summary: PurposeTo investigate the effects of a single dose of juice on physical performance, oxidative stress, inflammation and muscle damage in runners.Methods Fourteen recreational male runners (39 ± 9 years, VO2peak = 55.9 ± 6.5 ml/kg/min) performed two running tests to exhaustion at 80% of VO2max after ingesting grape juice or a placebo drink (10 ml/kg/day) randomly. Blood samples were taken before and 2 h after supplementation and immediately after running to analyze total antioxidant capacity (TAC), malondialdehyde (MDA), alpha-1 acid glycoprotein (A1GPA), high-sensitivity C-reactive protein (hs-CRP), creatine kinase (CK) and lactate dehydrogenase (LDH).ResultsThe participants ran for an average of 59.2 ± 27.8 min until exhaustion in the placebo group and for 68.4 ± 29.7 min until exhaustion in the grape juice intake group, which was a significantly longer time (p = 0.008). This improvement in physical performance was accompanied by a 43.6% increase in TAC (p = 0.000) at the post-exercise timepoint compared to the level at baseline. MDA, A1GPA, hs-CRP, CK, and LDH did not exhibit changes. In contrast, no significant change in any variable was observed after consuming the placebo drink.ConclusionThe single-dose intake of purple grape juice demonstrated an ergogenic effect in recreational runners by increas-ing run time to exhaustion and increasing antioxidant activity.

Publication year: 2019

Types of publication: Journal article

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