Phenolic-rich apple extracts have photoprotective and anti-cancer effect in dermal cells.
Phenolic-rich apple extracts have photoprotective and anti-cancer effect in dermal cells.
Author(s): RAPHAELLI, C. de O.; AZEVEDO, J. G.; PEREIRA, E. dos S.; VINHOLES, J. R.; CAMARGO, T. M.; HOFFMANN, J. F.; RIBEIRO, J. A.; VIZZOTTO, M.; ROMBALDI, C. V.; WINK, M. R.; BRAGANHOL, E.; NORA, L.
Summary: Skin cancer is the most common type of malignancy in light-skinned populations and phenolics are promising anticarcinogenic agents.To characterise and evaluate the protective potential of apple extracts against the DNA damage caused by UV-radiation in culture of human fibroblasts as well as to verify the anticarcinogenic effect of these extracts in murine and human melanoma cells.
Publication year: 2021
Types of publication: Journal article
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