Investigation of antifungal activity from Vismia guianensis (Aubl.) standardized extract.

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Author(s): RODRIGUES, I. C.; ALVES, P. P.; CHAVES, F. C. M.; KLUCZKOVSKI, A. M.; CORTEZ, A. C. A.; SOUZA, J. V. B. de; SOUZA, T. P. de

Summary: ABSTRACT: In the Amazon, the use of medicinal plants by native populations is an important source of ethnopharmacological knowledge. Vismia guianensis (Aubl.) Choisy is widely used against diseases caused by fungi. Thus, the aim of this work was to evaluate the antifungal potential of the species Vismia guianensis (Aubl.) Choisy and the influence of extractive parameters on the antifungal activity. Dried extracts were prepared from leaves and tested for activity against the fungal species Candida albicans, Malassezia furfur, and Trichophyton rubrum. The most promising extract was obtained with polar solvents (methanol and ethanol), and no significant difference was measured between the activities exhibited by these extracts (MIC 410 ?g/mL). RESUMO: Na Amazônia, o uso de plantas medicinais pelas populações nativas é uma importante fonte de conhecimento etnofarmacológico. Vismia guianensis (Aubl.) Choisy é amplamente utilizada contra doenças causadas por fungos. Assim, o objetivo deste trabalho foi avaliar o potencial antifúngico da espécie Vismia guianensis (Aubl.) Choisy e a influência de parâmetros extrativos na atividade antifúngica. Os extratos foram preparados a partir das folhas da espécie vegetal e testados quanto à atividade contra as espécies fúngicas Candida albicans, Malassezia furfur e Trichophyton rubrum. O extrato mais promissor foi obtido com solventes polares (metanol e etanol) e nenhuma diferença significativa foi encontrada entre as atividades exibidas por esses extratos (CIM 410 ?g/mL).

Publication year: 2024

Types of publication: Journal article

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