Overexpression of the Transcription Factor HAA1 to enhance Komagataella phaffii resistance to inhibitory compounds.
Overexpression of the Transcription Factor HAA1 to enhance Komagataella phaffii resistance to inhibitory compounds.
Author(s): PEDROSA, M. J.; FERREIRA, L. M. M.; PAES, B. G.; NAKAI, D. K.; DUARTE-BRANDAO, L. T.; ALMEIDA, J. R. M. de
Summary: The use of renewable feedstocks, like lignocellulosic biomass, is growing rapidly in industrial biotechnology because of its usage in bioprocesses. This biomass originates, principally, from agroindustry residues and can be used to obtain substances such as xylonic acid. Unfortunately, one of the biggest obstacles for the usage of lignocellulosic biomass is the microorganism response to inhibitory compounds found in renewable biomasses after they are pre-treated using hydrolyses, such as acetic acid and lignin derived aromatic compounds. Those can inhibit or even completely block the cell’s metabolic activity.
Publication year: 2024
Types of publication: Abstract in annals or event proceedings
Unit: Embrapa Agroenergy
Keywords: Biomass, Genetic engineering, Lignocellulosic wastes
Observation
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