Development and validation of a method for the analysis of Ochratoxin A in roasted coffee by liquid chromatography/electrospray-mass spectrometry in Tandem (LC/ESI-MS/MS).

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Author(s): BANDEIRA, R. D. C. C.; UEKANE, T. M.; CUNHA, C. P. da; GEAQUINTO, L. R. O.; CUNHA, V. S.; CAIXEIRO, J. M. R.; GODOY, R. L. O.; CRUZ, M. H. C. de la.

Summary: A method using LC/ESI-MS/MS for the quantitative analysis of Ochratoxin A in roasted coffee was described. Linearity was demonstrated (r = 0.9175). The limits of detection and quantification were 1.0 and 3.0 ng g-1, respectively. Trueness, repeatability and intermediate precision values were 89.0-108.8%; 2.4-13.7%; 12.5-17.8%, respectively. To the best of our knowledge, this is the first report in which Ochratoxin A in roasted coffee is analysed by LC/ESI-MS/MS, contributing to the field of mycotoxin analysis, and it will be used for future production of Certified Reference Material.

Publication year: 2012

Types of publication: Journal article

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