Anti-candidal activity and proteases inhibition of 7-Hydroxycalamenene isolated from Croton cajucara.

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Author(s): AZEVEDO, M. M. B.; ALMEIDA, C. A.; CHAVES, F. C. M.; SOARES, R. M. A.; BIZZO, H. R.; ALVIANO, C. S.; ALVIANO, D. S.

Summary: The leaves from Croton cajucara Benth. (family Euphorbiaceae), a shrub from the Amazon, have been locally used in folk medicine to treat diabetes, malaria, gastrointestinal and liver disorders. A chemotype of this species was found with an essential oil rich in 7-hydroxycalamenene. 7-hydroxycalamenene is a hydroxylated sesquiterpene found in Heritiera ornithocephala, Eremophila drummondii, Heteroscyphus planus, Tilia europea, Morus alba, Ulmus thomasii and other elm species, and methanolic and dichloromethanic extracts of Bazzania trilobata.

Publication year: 2013

Types of publication: Offprints

Keywords: Croton cajucara

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