Intensive production systems benefit the proliferation of phytopathogens and polyphagous insect pests by extending the period of host presence in the field.The chemical control of pests and diseases is the main tool used. Therefore, there is a relevant concern about the negative impacts of excessive dependence on only one control strategy. Questions such as: what are the effects of the excessive use of multisite fungicides on the soil microbiota; and which levels of metals (present in multisite fungicides) in the soil can cause toxicity to plants are still unanswered. In addition, dependence on chemical control can select populations of phytopathogens and pests resistant to the most used chemical groups.Therefore, it is essential that there are studies to monitor the susceptibility of pests and phytopathogens to the main chemical groups, as well as studies of these possible negative impacts of multisite fungicides. In addition, that new proposals for the management of diseases and pests common to soybeans and cotton, integrating chemical control with biological control, be proposed. This, then, is the general objective of the project.The project contains a Solution for innovation that includes research activities that provide information on the impacts of the use of multisite fungicides on the soil microbiota, on the levels of metals in the soil and the efficiency of the combination of chemical control with biological control of the target spot in soybean and in the cotton plant. A second activity will focus on the integration of chemical control with biological pest control. Finally, there is a susceptibility monitoring activity for the main polyphagous pests in the soy-cotton system to enhance chemical control by recommending better insecticide rotations for populations resistant to a given active ingredient.This project is expected to generate effective recommendations for the management of pests and diseases that are less dependent on the use of chemical control, thus contributing to the achievement of the objective of guaranteeing sustainable food production systems and implementing resilient agricultural practices, as set out in the Objective of UN Sustainable Development: Zero hunger and sustainable agriculture. (Google translation)