Black pepper ( Piper nigrum L.) is highly important in Brazilian agri-business, and it currently occupies the fourth position in the world's market export rates, the state of Pará being responsible for 85% of the national production. In this context, the emergence of fusariosis, caused by the Fusarium solani f. sp. Piperis fungus, has been the source of significant losses to the black pepper culture, especially in Pará. Studies have confirmed the narrow genetic base and the susceptibility to the pathogen in the evaluated BAG genotypes of black pepper from Oriental Amazon Embrapa, having been identified nine species of Piper sp. native from the Amazon which are resistant to the fungus. The use of these species has been encouraged in programs of conventional improvement of the black pepper tree. Studies involving inter-specific crossbreeding between P. nigrum and resistant native species have been showing difficulty to obtain hybrids , and consequently, further difficulties in conducting programs of conventional development. Other researches which involved obtaining grafts have resulted in incompatibility between vascular systems of the black pepper tree and the native Piper sp. species. Although many studies have been proposed in order to circumvent this problem, so far no strategies have offered definitive solution to the fusariosis problem. This project aims to identify putative gene sequences which are involved in the interaction between an Amazon native Piper sp. species and the pathogen Fusarium solani, since few studies have been developed in a molecular level. The information will be acquired through the Solid sequencing platform, along with Pará's Federal University' gene team. This research is included in the approved project of Pará's Gene and Protein Network headed by UFPA, aiming to offer genetic information to support black pepper's improvement program.