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A rapid primary screening method for antitumor using the oomycete Pythium aphanidermatum. Author(s): SANTOS, S. N.; MELO, I. S. de Investigating bioactive components from microbial metabolites can provide potential source for drug discovery. There are a number of traditional antitumor compounds screening assays already described.... ... Repository: BDPA Publication year: 2016
Purification, characterization and evaluation of the antitumoral activity of a phospholipase A2 from the snake Bothrops moojeni. Author(s): FRIHLING, B. E. F.; BOLETI, A. P. de A.; OLIVEIRA, C. F. R. de; SANCHES, S. C.; CARDOSO, P. H. de O.; VERBISCK, N. V.; MACEDO, M. L. R.; SANTA RITA, P. H.; CARVALHO, C. M. E.; MIGLIOLO, L. Nature presents a wide range of biomolecules with pharmacological potential, including venomous animal proteins. Among the protein components from snake venoms, phospholipases (PLA2) are of great impo... ... Repository: BDPA Publication year: 2022
Antitumor Effects of Freeze-Dried Robusta Coffee (Coffea canephora) Extracts on Breast Cancer Cell Lines. Author(s): NIGRA, A. D.; GUIMAREAES, D. de A. B.; PRUCCA, C. G.; FREITAS-SILVA, O.; TEODORO, A. J.; GIL, G. A. Coffee consumption is believed to have chemopreventive and chemotherapeutic effects and to contribute to preventing thedevelopment and progression of cancer. However, there is still controversy around... ... Repository: BDPA Publication year: 2021
Antitumoral, antioxidant and antimicrobial molecules from combretum rupicola. Author(s): SANTOS, S. N.; KAVAMURA, V.; CASTANHA, R. F.; ANDREOTE, F. D.; CARVALHO, J. E.; QUEIROZ, S. C. do N. de; MELO, I. S. de This investigation describes the anticancer, antioxidant and antimicrobial properties of the extracts of Combretum rupicola, a native plant from Northeast of Brazil. Methanolic, ethyl acetate and chlo... ... Repository: BDPA Publication year: 2013
Arylated and dihydrofuran naphthoquinones: electrochemical parameters, evaluation of antitumor activity and their correlation. Author(s): FERREIRA, F. da R.; FERREIRA, S. B.; ARAÚJO, A. J.; MARINHO FILHO, J. D. B.; PESSOA, C.; MORAES, M. O.; COSTA-LOTUFO, L. V.; MONTENEGRO, R. C.; SILVA, F. de C. da; FERREIRA, V. F.; COSTA, J. G. da; ABREU, F. C. de; GOULART, M. O. F. Repository: BDPA Publication year: 2013
Síntese, caracterização e estudo da atividade fungicida e antitumoral de novas dialquilfosfonilacilidrazonas. Author(s): BARBOZA, H. T. G. O trabalho apresentado refere-se a síntese de dialquilfosfonilacilidrazonas inéditas que ocorreu em 3 etapas: a primeira etapa consistiu na síntese de diferentes fosfonoacetatos de dialquila obtidos p... ... Repository: BDPA Publication year: 2018
Atividade antitumoral de biomoléculas obtidas de Fusarium oxysporum, um endofítico de Combretum leprosum, planta nativa do semiárido brasileiro. Author(s): SANTOS, S. N.; FERRARIS, F. K.; KAVAMURA, V.; TAKETANI, R. G.; LANÇONI, M. D.; DINI-ANDREOTE, F.; HENRRIQUES, M. das G. M. O.; MELO, I. S. de Repository: BDPA Publication year: 2011
Actinobacteria from Antarctica as a source for anticancer discovery. Author(s): SILVA, L. J. da; CREVELIN, E. J.; SOUZA, D. T.; LACERDA JÚNIOR, G. V.; OLIVEIRA, V. M.; RUIZ, A. L. T. G.; ROSA, L. H.; MORAES, L. A. B.; MELO, I. S. de Abstract: Although many advances have been achieved to treat aggressive tumours, cancer remains a leading cause of death and a public health problem worldwide. Among the main approaches for the discov... ... Repository: BDPA Publication year: 2020
Anthocyanins formulated with carboxymethyl starch for gastric and intestinal delivery. Author(s): SABINO, L. B. de S.; COPES, F.; SAULAIS, S.; BRITO, E. S. de; SILVA JÚNIOR, I. J. da; LE, T. C.; MATEESCU, M. A.; MANTOVANI, D. Anthocyanins obtained from jambolan have been used as active agents in different carboxymethyl starch-based tablet formulations and their release profiles evaluated in simulated gastric fluids (SGF) a... ... Repository: BDPA Publication year: 2022
Carotenoides Pro-vitamina A em frutos de bananeira. Author(s): BORGES, C. V.; RAMLOV, F.; KUHNEN, S.; MARASCHIM, M. Os tipos de carotenóides variam muito nas frutas, sendo que aproximadamente 50 carotenóides possuem atividade pró-vitamina A. Dentre esses o β-caroteno é o mais importante e abundante em alimento... ... Repository: BDPA Publication year: 2012

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