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Detection of antileukemia metabolites from P. limosum integrating genome mining, metabolomic analysis and cytotoxicity assays. Author(s): BASSICHETO, M.; OLIVEIRA, C.; RIVERO, M.; SIPOLONI, V.; SOARES, J. K. C.; SILVA, G. F. da; JUSTO, G.; VEIGA, T.; SOMAN, L. Chemical dereplication and genome mining approaches were applied to detect cytotoxic metabolites produced by P. limosum CMLD 19 with anticancer potential against human leukemia cells. During the ongoi... ... Repository: BDPA Publication year: 2023
Botrytis cinerea: acetylcholinesterase inhibition, cytotoxicity, antimicrobial, larvicidal activity and metabolite isolated from fungal extract. Author(s): OLIVEIRA, M. de; SILVA, C. B. da; HIROTA, B. C. K.; OLIVEIRA, C. F. de; RECH, K. S.; PAULA, C. da S.; DIAS, J. de F. G.; MIGUEL, O. G.; AUER, C. G.; MIGUEL, M. D. This study highlights the importance of fungi, specifically Botrytis cinerea Pers., in the search for bioactive compounds with therapeutic potential. Extraction approaches using Soxhlet, and maceratio... ... Repository: BDPA Publication year: 2024
Winery by-products: extraction optimization, phenolic composition and cytotoxic evaluation to act as a new source of scavenging of reactive oxygen species. Author(s): MELO, P. S.; MASSARIOLI, A. P.; DENNY, C.; SANTOS, L. F. dos; FRANCHIN, M.; PEREIRA, G. E.; VIEIRA, T. M. F. de S.; ROSALEN, P. L.; ALENCAR, S. M. de This study aimed to assess the antioxidant potential of optimized extracts of winery by-products, which was measured using the scavenging capacity of synthetic free radicals and reactive oxygen specie... ... Repository: BDPA Publication year: 2015
Cytotoxic Effects of Extract of Acmella Oleraceae (Jambú) in Rhipicephalus Microplus Female Ticks. Author(s): OLIVEIRA, P. R. de; CASTRO, K. N. de C.; ANHOLETO, L. A.; MATHIAS, M. I. C. Repository: BDPA Publication year: 2016
Antiproliferative and cytotoxic effects of purple pitanga (Eugenia uniflora L.) extract on activated hepatic stellate cells. Author(s): DENARDIN, C. C.; PARISI, M. M.; MARTINS, L. A. M.; TERRA, S. R.; BOROJEVIC, R.; VIZZOTTO, M.; PERRY, M. L.; EMANUELLI, T.; GUMA, F. T. C. R. Repository: BDPA Publication year: 2013
Metabolomics-based discovery of biomarkers with cytotoxic potential in extracts of Myracrodruon urundeuva. Author(s): CASTRO, C. B. DE; LUZ, L. DOS R.; GUEDES, J. A. C.; PORTO, D. D.; SILVA, M. F. S.; SILVA, G. S. DA; RIBEIRO, P. R. V.; CANUTO, K. M.; BRITO, E. S. de; ZAMPIERI, D. DE S.; PESSOA, C. do Ó.; ZOCOLO, G. J. Myracrodruon urundeuva (aroeira-do-sertão) is a species threatened with extinction due to anthropogenic exploitation. Phytochemical analysis of bark, branch and leaf extracts revealed the presence of... ... Repository: BDPA Publication year: 2020
Evaluation of cytotoxicity features of antimicrobial peptides with potential to control bacterial diseases of citrus. Author(s): KISHI, R. N. I.; STACH-MACHADO, D.; SINGULANI, J. de L.; SANTOS, C. T. dos; FUSCO-ALMEIDA, A. M.; CILLI, E. M.; ASTUA, J. de F.; PICCHI, S. C.; MACHADO, M. A. considered an alternative for pesticides used to control plant pathogens, including those affecting citrus. Brazil is the largest producer and exporter of frozen concentrated orange juice in the world... ... Repository: BDPA Publication year: 2018
Antioxidant, anti-acetylcholinesterase and cytotoxic activities of ethanol extracts of peel, pulp and seeds of exotic Brazilian fruits Antioxidant, anti-acetylcholinesterase and cytotoxic activities in fruits. Author(s): OMENA, C. M. B.; VALENTIM, I. B.; GUEDES, G. da S.; RABELO, L. A.; MANO, C. M.; BECHARA, E. J. H.; SAWAYA, A. C. H. F.; TREVISAN, M. T. S.; COSTA, J. G. da; FERREIRA, R. C. S.; SANTANA, A. E. G.; GOULART, M. O. F. Ethanol extracts of powdered genipap (Genipa americana L.), umbu (Spondia tuberosa A.) and siriguela (Spondia purpurea L.) prepared from separate pulp, seeds and peel were investigated for their (i) a... ... Repository: BDPA Publication year: 2012
Apple extract: cytotoxicity and dna protection. Author(s): VIZZOTTO, M.; FERRI, N. M. L.; BIALVES, T. S.; ARAUJO, V. F.; PEREIRA, E. dos S.; KROLOW, A. C. R. Repository: BDPA Publication year: 2013
Cytotoxic and genotoxic effects of Macroptilium lathyroides. Author(s): SILVA, M. S. A.; YAMASHITA, O. M.; ROSSI, A. A. B.; CONCENCO, G.; CARVALHO, M. A. C.; FELITO, R. A. Repository: BDPA Publication year: 2018

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