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Novel putative causal mutations associated with fat traits in Nellore cattle uncovered by eQTLs located in open chromatin regions. Author(s): GARCIA, I. S.; VIGNATO, B. S.; CESAR, A. S. M.; PETRINI, J.; SILVA, V. H. DA; MOROSINI, N. S.; GOES, C. P.; AFONSO, J.; SILVA, T. R. DA; LIMA, B. D.; CLEMENTE, L. G.; REGITANO, L. C. de A.; MOURÃO, G. B.; COUTINHO, L. L. Intramuscular fat (IMF) and backfat thickness (BFT) are critical economic traits impacting meat quality. However, the genetic variants controlling these traits need to be better understood. To advance... ... Repository: BDPA Publication year: 2024
Expression quantitative trait loci (eQTL) hotspot regions from whole genome analysis of Nellore steers. Author(s): CESAR, A. S. M.; REGITANO, L. C. de A.; LANNA, D. P. D.; POLETI, M. D.; KOLTES, J. E.; REECY, J. M.; FRITZ-WATERS, E.; KRAMER, L.; GARRICK, D.; MUDADU, M. de A.; TULLIO, R. R.; COUTINHO, L. L. Repository: BDPA Publication year: 2016
Identification of putative regulatory regions and transcription factors associated with intramuscular fat content traits. Author(s): CESAR, A. S. M.; REGITANO, L. C. de A.; REECY, J. M.; POLETI, M. D.; OLIVEIRA, P. S. N.; OLIVEIRA, G. B. de; MOREIRA, G. C. M.; MUDADU, M. de A.; TIZIOTO, P. L.; KOLTES, J. E.; Fritz-Waters, E.; KRAMER, L.; GARRICK, D.; BEIKI, H.; GEISTLINGER, L.; MOURÃO, G. B.; ZERLOTINI NETO, A.; COUTINHO, L. L. Background: Integration of high throughput DNA genotyping and RNA-sequencing data allows for the identification of genomic regions that control gene expression, known as expression quantitative trait... ... Repository: BDPA Publication year: 2018
Multi-omics data elucidate parasite-host-microbiota interactions and resistance to Haemonchus contortus. in sheep. Author(s): NICIURA, S. C. M.; CARDOSO, T. F.; IBELLI, A. M. G.; OKINO, C. H.; ANDRADE, B. G.; BENAVIDES, M. V.; CHAGAS, A. C. de S.; ESTEVES, S. N.; MINHO, A. P.; REGITANO, L. C. de A.; GONDRO, C. The integration of molecular data from hosts, parasites, and microbiota can enhance our understanding of the complex biological interactions underlying the resistance of hosts to parasites. Haemonchus... ... Repository: BDPA Publication year: 2024
Genome-wide linkage analysis of global gene expression in loin muscle tissue identifies candidate genes in pigs. Author(s): STEIBEL, J. P.; BATES, R. O.; ROSA, G. J. M.; TEMPELMAN, R. J.; RILINGTON, V. D.; RAGAVENDRAN, A.; RANEY, NANCY E.; RAMOS, A. M.; CARDOSO, F. F.; EDWARDS, D. B.; ERNST, C. W. Background: Nearly 6,000 QTL have been reported for 588 different traits in pigs, more than in any other livestock species. However, this effort has translated into only a few confirmed causative vari... ... Repository: BDPA Publication year: 2011
Integrative analysis between genome-wide association study and expression quantitative trait Loci reveals bovine muscle gene expression regulatory polymorphisms associated with intramuscular fat and backfat thickness. Author(s): VIGNATO, B. S.; CESAR, A. S. M.; AFONSO, J.; MOREIRA, G. C. M.; POLETI, M. D.; PETRINI, J.; GARCIA, I. S.; CLEMENTE, L. G.; MOURÃO, G. B.; REGITANO, L. C. de A.; COUTINHO, L. L. Understanding the architecture of gene expression is fundamental to unravel the molecular mechanisms regulating complex traits in bovine, such as intramuscular fat content (IMF) and backfat thickness... ... Repository: BDPA Publication year: 2022
Global assessment of imprinted gene expression in the bovine conceptus by next generation sequencing. Author(s): CHEN, Z.; HAGEN, D. E.; WANG, J.; ELSIK, C. G.; JI, T.; SIQUEIRA, L. G. B.; HANSEN, P. J.; RIVERA, R. M. Abstract Genomic imprinting is an epigenetic mechanism that leads to parental-allele-specific gene expression. Approximately 150 imprinted genes have been identified in humans and mice but less than 3... ... Repository: BDPA Publication year: 2016
Novel polymorphisms in the PLIN2 gene of Nellore cattle. Author(s): DEFANT, H.; MEIRA, A. N.; COUTINHO, L. L.; REGITANO, L. C. de A.; POLETI, M. D.; MOREIRA, G. C. M.; PADUAN, M.; MARIANI, P.; ZERLOTINI NETO, A.; MOURÃO, G. B.; CESAR, A. S. M. ABSTRACT. Genetic variations in genes involved in lipid storage, which also may interfere with important phenotypic traits such as intramuscular fat deposition in cattle, can represent useful markers... ... Repository: BDPA Publication year: 2019
Potential biomarkers for feed efficiency-related traits in nelore cattle identified by co-expression network and integrative genomics analyses. Author(s): LIMA, A. O. de; KOLTES, J. E.; DINIZ, W. J. S.; OLIVEIRA, P. S. N. de; CESAR, A. S. M.; TIZIOTO, P. L.; AFONSO, J.; SOUZA, M. de S.; PETRINI, J.; ROCHA, M. I. P.; CARDOSO, T. F.; ZERLOTINI NETO, A.; COUTINHO, L. L.; MOURÃO, G. B.; REGITANO, L. C. de A. Feed efficiency helps to reduce environmental impacts from livestock production, improving beef cattle profitability. We identified potential biomarkers (hub genes) for feed efficiency, by applying co... ... Repository: BDPA Publication year: 2020
Detection of Co-expressed pathway modules associated with mineral concentration and meat quality in nelore cattle. Author(s): DINIZ, W. J. S.; MAZZONI, G.; COUTINHO; BANERJEE, P.; GEISTLINGER, L.; CESAR, A. S. M.; BERTOLINI. F.; AFONSO, J.; OLIVEIRA, P. S. N.; TIZIOTO, P. C.; KADARMIDEEN, H. N.; REGITANO, L. C. de A. Meat quality is a complex trait that is influenced by genetic and environmental factors, which includes mineral concentration. However, the association between mineral concentration and meat quality,... ... Repository: BDPA Publication year: 2019

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