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An in silico approach for the antigenic mutation and immune memory. Author(s): CASTRO, A. de; FRONZA, C. F.; ALVES, D. The this article we studied in machina an approach to simulate the process of antigenic mutation. Our results have suggested that the durability of the immune memory is affected by process of antigeni... ... Repository: BDPA Publication year: 2009
In silico approach for viral mutations and sustainability of immunizations. Author(s): CASTRO, A. de In this paper we use virtual samples of individuals and a dynamical modeling proposed in a previous study to study the behavior of immune memory against antigenic mutation. Repository: BDPA Publication year: 2015
Analysing nonsynonymous mutations between two Mycobacterium bovis strains with contrasting pathogenic profiles. Author(s): BIGI, M.; VAZQUEZ, C. L.; CASTELÃO, A. B. C.; GARCÍA, E. A.; CATALDI, A. A.; JACKSON, M.; MAcNEIL, M.; SORIA, M.; ZUMÁRRAGA, M. J.; MATIAS, C.; GAGO, G.; BLANCO, F. C.; NISHIBEF, C.; ALMEIDA, N. F.; ARAUJO, F. R.; BIGI, F. Mycobacterium bovis (M. bovis) is the causative agent of bovine tuberculosis, a chronic infectious disease that can affect cattle, other domesticated species, wild animals and humans. This disease pro... ... Repository: BDPA Publication year: 2019
Molecular homologous modeling of 3B-HSD2 mutant enzyme: structure-function aspects of Pro222GLN mutation correlates with the experimental data from a patient with congenital adrenal hyperplasia. Author(s): FERRAZ, L. F. C.; SOARDI, F.; FALCÃO, P.; NESHICH, G.; MELLO, M. P. de Short abstract: We describe the mutation Pro222GIn in HSD3B2 gene on a patient with congenital adrenal hyperplasia. Molecular modeling of 3B-HSD2 mutant allowed us to identify critical role of residue... ... Repository: BDPA Publication year: 2006
Identification of mutations in a QTL region on chromosome 3 associated with fatness in chickens. Author(s): MOREIRA, G. C. M.; GODOY, T. F.; BOSCHIERO, C.; LEDUR, M. C.; GASPARIN, G.; ANDRADE, S. C. da S.; PADUAN, M.; COUTINHO, L. L. Repository: BDPA Publication year: 2013
Studies on variation of carotenoid-proteins content in Cassava (Manihot esculenta Crantz) storage root reveal implications for breeding and the use of induced mutations. Author(s): CARVALHO, L. J. C. B.; ALMEIDA, J. D. de; ANDERSON, J. V.; VIEIRA, E. A.; CHEN, S.; SOUZA, C. R. B. de; FUHRMANN, E.; SILVA, J. P. da Carotenoid-Protein content in cassava storage root (CSR) is low but variable, and characterization of this variability is lacking. Accumulation of carotenoids occurs in chromoplast and depends on a br... ... Repository: BDPA Publication year: 2013
A nonsense mutation in the tyrosinase gene causes albinism in water buffalo. Author(s): DAME, M. C. F.; XAVIER, G. M.; OLIVEIRA FILHO, J. P.; BORGES, A. S.; OLIVEIRA, H. N.; RIET-CORREA, F.; SCHILD, A. L. Background: Oculocutaneous albinism (OCA) is an autosomal recessive hereditary pigmentation disorder affecting humans and several other animal species. Oculocutaneous albinism was studied in a herd of... ... Repository: BDPA Publication year: 2012
Deviation from Mendelian transmission of autosomal SNPs can be used to estimate germline mutations in humans exposed to ionizing radiation. Author(s): LEITE FILHO, H. P.; PINTO, I. P.; OLIVEIRA, L. G.; COSTA, E. O. A.; CRUZI, A. S. da; SILVA, D. de M. e; SILVA, C. C. da; CAETANO, A. R.; CRUZ, A. D. da Repository: BDPA Publication year: 2020
Mutations in the capsid protein of porcine circovirus type 2 indicates a viral immune evasion. Author(s): GAVA, D.; SCHAEFER, R.; SERRÃO, V. H. B.; CANTAO, M. E.; SILVA, M. C.; ZANELLA, J. R. C. Repository: BDPA Publication year: 2014
A differential phenotypic expression of a divergent spindle mutation in interspecific Brachiaria hybrids. Author(s): FELISMINO, M. F.; PAGLIARINI, M. S.; VALLE, C. B. do Several mutations are known to alter the normal progression of meiosis and can be correlated with defects in microtubule distribution. The dv mutation affects the spindle organization and chromosomes... ... Repository: BDPA Publication year: 2008

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