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Detection of antileukemia metabolites from P. limosum integrating genome mining, metabolomic analysis and cytotoxicity assays. Author(s): BASSICHETO, M.; OLIVEIRA, C.; RIVERO, M.; SIPOLONI, V.; SOARES, J. K. C.; SILVA, G. F. da; JUSTO, G.; VEIGA, T.; SOMAN, L. Chemical dereplication and genome mining approaches were applied to detect cytotoxic metabolites produced by P. limosum CMLD 19 with anticancer potential against human leukemia cells. During the ongoi... ... Repository: BDPA Publication year: 2023
Botrytis cinerea: acetylcholinesterase inhibition, cytotoxicity, antimicrobial, larvicidal activity and metabolite isolated from fungal extract. Author(s): OLIVEIRA, M. de; SILVA, C. B. da; HIROTA, B. C. K.; OLIVEIRA, C. F. de; RECH, K. S.; PAULA, C. da S.; DIAS, J. de F. G.; MIGUEL, O. G.; AUER, C. G.; MIGUEL, M. D. This study highlights the importance of fungi, specifically Botrytis cinerea Pers., in the search for bioactive compounds with therapeutic potential. Extraction approaches using Soxhlet, and maceratio... ... Repository: BDPA Publication year: 2024
Cytotoxic activity of fungal metabolites from the Pathogenic Fungus Beauveria bassiana: an intraspecific evaluation of beauvericin production. Author(s): VALENCIA, J. W. A.; BUSTAMANTE, A. L. G.; JIMÉNEZ, A. V.; SA, M. F. G. de Repository: BDPA Publication year: 2011
Red sacaca essential oil-loaded nanostructured lipid carriers optimized by factorial design: cytotoxicity and cellular reactive oxygen species levels. Author(s): CHURA, S. S. D.; MEMÓRIA, K. A. S.; LOPES, A. T.; PELISSARI, F. M.; SILVEIRA, J. V. W. da; BEZERRA, J. de A.; CHAVES, F. C. M.; RODRIGUES, A. P.; FARIA, J. A. Q. A.; CARNEIRO, G. Amazonian flora includes several species with the potential to develop pharmaceutical and biotechnological products. The essential oils from Amazonian species possess some biological properties, such... ... Repository: BDPA Publication year: 2023
A rapid primary screening method for antitumor using the oomycete Pythium aphanidermatum. Author(s): SANTOS, S. N.; MELO, I. S. de Investigating bioactive components from microbial metabolites can provide potential source for drug discovery. There are a number of traditional antitumor compounds screening assays already described.... ... Repository: BDPA Publication year: 2016
Early detection and classification of Carica papaya fungi trough the analysis of volatile metabolites by gas chromatography and chemometrics. Author(s): TERRA, L. R.; QUEIROZ, S. C. do N. de; TERAO, D.; FERREIRA, M. M. C. Papaya (Carica papaya) is a fruit widely consumed in the world due to its pleasant taste and high nutritional value. Brazil stands out as one of the world?s largest producers and exporters of papaya.... ... Repository: BDPA Publication year: 2019
Ruminal metabolic parameters and milk fatty acid profile of cows grazing Marandu grass supplemented with roasted soybeans. Author(s): MOURTHÉ, M. H. F.; LOPES, F. C. F.; REIS, R. B.; GAMA, M. A. S. da; MORENZ, M. J. F.; SALOMÃO, B. M. Abstract The goal of this study was to evaluate the ruminal metabolic parameters and milk fatty acid composition of cows managed under continuous grazing on Marandu grass. Four rumen-cannulated Holste... ... Repository: BDPA Publication year: 2019
Evaluation of the proliferation of dedifferentiated cells of yellow bell pepper (Capsicum annuum cv. Pimentão amarelo). Author(s): SANTOS, M. R. A. dos; SOUZA, P. G. Capsicum annuum is notable for its secondary metabolites, which can be of great interest for use in agriculture as alternatives to agrochemicals. Cell suspensions have been used for in vitro largescal... ... Repository: BDPA Publication year: 2017
Proliferation of dedifferentiated cells from internodes of bell pepper (Capsicum annuum cv. Yolo wonder). Author(s): SANTOS, M. R. A. dos; SMOZINSK, C. V. The aim of this study was to dedifferentiate cells of internodes of Capsicum annuum cv. Yolo Wonder into calluses, supplementing the culture medium with the growth regulators 2,4-D (0, 4.52, 9.05 and... ... Repository: BDPA Publication year: 2017
Chemical and biological evaluation of Amazonian medicinal plant Vouacapoua americana Aubl. Author(s): ÇIÇEK, S. S.; BARBOSA, A. L. P.; WENZEL-STORJOHANN, A.; SEGOVIA, J. F. O.; BEZERRA, R. M.; SÖNNICHSEN, F.; ZIDORN, C.; KANZAKI, I.; TASDEMIR, D. Vouacapoua americana (Fabaceae) is an economically important tree in the Amazon region and used for its highly resistant heartwood as well as for medicinal purposes. Despite its frequent use, phytoche... ... Repository: BDPA Publication year: 2023

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