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Exploring the potential biological activities and chiral composition of Lippia origanoides Kunth essential oil: inhibition of enzymes linked to Alzheimer’s disease and Type 2 diabetes. Author(s): PAVARINO, M.; CAGLIERO, C.; MARENGO, A.; BICCHI, C.; BIZZO, H. R.; CHAVES, F. C. M.; RUBIOLO, P.; SGORBINI, B. Diabetes mellitus and Alzheimer’s disease (AD) are increasingly common in ageing population. Type 2 diabetes is an important risk factor for AD due to shared phenotypes, including mitochondrial dysfun... ... Repository: BDPA Publication year: 2024
Eugenia punicifolia leaf extract has a hypotensive effect and inhibits angiotensin-converting enzyme activity in both in vitro and in vivo models. Author(s): GALENO, D. M. L.; NASCIMENTO, O. V. do; ARAÚJO, M. S. B. de; SOUZA, T. P. de; SILVA, E. L.; CARVALHO, R. P.; CHIONG NETO, F. V.; SANTOS, R. H.; ANDRADE, Z. G. de; CORRÊA, J. W. do N.; SILVA, F. M. A. da; KOOLEN, H. H. F.; PINHEIRO, C. C.; CHAVES, F. C. M. Chronic high blood pressure has for many years been considered a public health problem. Eugenia punicifolia is a plant used to treat diabetes by the local population, however its hypotensive effect ha... ... Repository: BDPA Publication year: 2020
Enzyme-assisted extraction of phenolics from winemaking by-products: Antioxidant potential and inhibition of alpha-glucosidase and lipase activities. Author(s): CAMARGO, A. C. de; REGITANO-D’ARCE, M. A. B.; BIASOTO, A. C. T.; SHAHIDI, F. Phenolics in food and agricultural processing by-products exist in the soluble and insoluble-bound forms. The ability of selected enzymes in improving the extraction of insoluble-bound phenolics from... ... Repository: BDPA Publication year: 2016
Identification of an alpha-amylase inhibitor from Pterodon pubescens with ability to inhibit Cowpea weevil digestive enzymes. Author(s): SILVA, D. P.; CASADO-FILHO, E. L.; CORRÊA, A. S. R.; FARIAS, L. R.; BLOCH JUNIOR, C.; GROSSI DE SÁ, M. F.; MENDES, P. A. M.; QUIRINO, B. F.; NORONHA, E. F.; FRANCO, O. L. Repository: BDPA Publication year: 2007
Biochemical characterisation of a Kunitz-type inhibitor from Tamarindus indica L. seeds and its efficacy in reducing plasma leptin in an experimental model of obesity. Author(s): MEDEIROS, A. F. de; COSTA, I. de S.; CARVALHO, F. M. C. de; KIYOTA, S.; SOUZA, B. B. P. de; SIFUENTES, D. N.; SERQUIZ, R. P.; MACIEL, B. L. L.; UCHÔA, A. F.; SANTOS, E. A. dos; MORAIS, A. H. de A. Repository: BDPA Publication year: 2018
Proteinase inhibition using small Bowman-Birk-type structures. Author(s): FERNANDEZ, J. H.; MELLO, M. O; GALGARO, L.; TANAKA, A. S.; SILVA-FILHO, M. C.; NESHICH, G. Absttract . Bowman-Birk inhibitors (BBIs) are cysteine-rich and highly cross-linked small proteins that function as specific pseudosubstrates for digestive proteinases. They typically display a "doubl... ... Repository: BDPA Publication year: 2007
Enhancement of Trichoderma harzianum CFAM-422 for cellulase and hemicellulase production by deletion of the carbon catabolite repressor gene cre1. Author(s): TAMIETTI, M. S.; MIDORIKAWA, G. E. O.; MENDES, T. D.; DAMASO, M. C. T.; BOM, E. P. S.; SILVA, A. S.; GOTTSCHALK, L. M. F.; NORONHA, E. F.; FAVARO, L. C. de L. Carbon catabolite repression (CCR) is a mechanism by which microorganisms can utilize preferably highly energetic compounds over those of difficult degradation. For Trichoderma reesei, the protein tha... ... Repository: BDPA Publication year: 2017
Evaluation of agroindustrial residues as substrates for cellulolytic enzymes production under solid state fermentation. Author(s): RODRIGUEZ-ZUNIGA, U. F.; LEMO, V.; FARINAS, C. S.; BERTUCCI NETO, V.; COURI, S. Repository: BDPA Publication year: 2008
Purification and characterization of a peroxidase present in xilopodium exsudates of umbu plants (Spondias tuberosa A.). Author(s): PINTO, M. dos S. T.; RIBEIRO, J. M.; ARAUJO, F. P. de; MELO, N. F. de; FERNANDES, K. V. S. Umbu plants are drought resistant trees which are able to store water and several other substances into its adapted root, named xylopodium. The exsudate from xilopodium is a natural solution rich in s... ... Repository: BDPA Publication year: 2015
Analysis of binding properties and specificity through identification of the interface forming residues (IFR) for serine proteases in silico docked to different inhibitors. Author(s): RIBEIRO, C.; TOGAWA, R. C.; NESHICH, I. A. P.; MAZONI, I.; MANCINI, A. L.; MINARDI, R. C. de M.; SILVEIRA, C. H. da; JARDINE, J. G.; SANTORO, M. M.; NESHICH, G. Background: Enzymes belonging to the same super family of proteins in general operate on variety of substrates and are inhibited by wide selection of inhibitors. In this work our main objective was to... ... Repository: BDPA Publication year: 2010

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