Protein-protein interactions virtually regulate all processes inside cells, e.g. signal transduction, metabolic regulation, gene regulation, and immunological responses which occur in a specific way. Several experimental methods are capable of detecting interactions between proteins, which can range from cellular "resolution" to experiments which expose atom level interactions. However, the performance of these combined experiments which generate complete information regarding the network of pro ...

Status: Completed     Start date: Sat Aug 01 00:00:00 GMT-03:00 2009

The identification of economically relevant genes might translate into considerable competitive advantage in markets more and more competitive and globalized. Genes which are associated with plague resistance, productivity increase and organoleptic attributes (which can be experienced by the senses such as color, taste and texture) appreciated by consumers are extremely important to the Brazilian stockbreeding market. There is a considerable number of bioinformatic tools that are available to th

Status: Completed     Start date: Tue Jan 01 00:00:00 GMT-03:00 2008

Enzymes have their function essentially determined by specific residue known as catalytic residue. Most methods to predict enzyme catalytic residue uses at least one criterion of primary sequence conservation. Considering that the function is a product of the structure, this project aims to identify among the structural descriptors available in the Sting software database those of higher relevance in the discrimination of catalytic residue. Thus, the project will propose a new enzyme classificat

Status: Completed     Start date: Sun Aug 01 00:00:00 GMT-03:00 2010

Computation used as a tool by scientific research has revolutionized the biological sciences, as it has done with many other fields of science, and considering the exponentially increasing amount and complexity of the scientific data being generated and needing to be efficiently handled, translated, processed and communicated, new computational resources are needed for the effective treatment of all this volume of data that makes it possible to transform it into knowledge and subsequently, as th

Status: Completed     Start date: Fri Apr 01 00:00:00 GMT-03:00 2011