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Author(s): LOPES FILHO, J. H.; SILVA, V. C. H. da; SANTOS, J. C. dos; DANTE, R. A.; GERHARDT, I. R.; YASSITEPE, J. E. de C. T.; FERNANDES, F. R.

Present and future challenges of modern agriculture. Gene editing tools for precision crop breeding. Genome editing methodologies. Origin of the CRISPR/Cas technology. Overview of mechanisms and enzym... ...

Repository: BDPA     Publication year: 2021

Author(s): PRADO, G. S.; PINHEIRO, T. T.; FARIA, J. C. de; VIANELLO, R. P.

We will focus here on the use of the CRISPR/Cas system to induce mutations via NHEJ. The NHEJ mechanism acts in most of the cell cycle and is not based on homology to repair DNA, causing mutations suc... ...

Repository: BDPA     Publication year: 2021

Author(s): SILVA, N. V. e; ANGELOTTI-MENDONÇA, J.; BARBOSA, E. G. G.; GIROTTO, L.; MOLINARI, M. D. C.; MERTZ-HENNING, L. M.; NEPOMUCENO, A. L.

Repository: BDPA     Publication year: 2021

Author(s): HERNANDES-LOPES, J.; YASSITEPE, J. E. de C. T.; KOLTUN, A.; PAUWELS, L.; SILVA, V. C. H. da; DANTE, R. A.; GERHARDT, I. R.; ARRUDA, P.

In this review, we discuss the advances in genome editing in crops with a particular focus on the use of technologies to improve complex traits such as water use efficiency, drought stress, and yield... ...

Repository: BDPA     Publication year: 2023

Author(s): VIEIRA, L. R.; FREITAS, N. C.; JUSTEN, F.; MIRANDA, V. de J.; GARCIA, B. de O.; NEPOMUCENO, A. L.; FUGANTI-PAGLIARINI, R.; FELIPE, M. S. S.; MOLINARI, H. B. C.; VELINI, E. D.; PINTO, E. R. de C.; DAGLI, M. L. Z.; ANDRADE, G.; FERNANDES, P. M. B.; MERTZ-HENNING, L. M.; KOBAYASHI, A. K.

The regulation of the use of products obtained through genome-editing techniques has been the subject of great debate worldwide. Currently, the discussions are mainly focused on whether products obtai... ...

Repository: BDPA     Publication year: 2021

Author(s): MOLINARI, H. B. C.; VIEIRA, L. R.; SILVA, N. V. e; PRADO, G. S.; LOPES FILHO, J. F.

Chapter 1: Introduction to genome editing in plants. Chapter 2: Genome editing via non-homologous end-joining (NHEJ) and ribonucleoproteins (RNP). Chapter 3: Genome editing by CRISPR/Cas via homologou... ...

Repository: BDPA     Publication year: 2021

Author(s): OLIVEIRA, K. E. S. de; RIBEIRO, C.; CARNEIRO, A. A.; CARNEIRO, N. P.

ABSTRACT - The CRISPR/Cas9 system is a gene editing method capable of accurately locating and altering a specific sequence of a genome. Currently, this technique stands out as a promising biotechnolog... ...

Repository: BDPA     Publication year: 2022

Author(s): PRADO, G. S.; ROCHA, D. C.; SANTOS, L. N. dos; CONTILIANI, D. F.; NOBILE, P. M.; MARTINATI-SCHENK, J. C.; PADILHA, L.; MALUF, M. P.; LUBINI, G.; PEREIRA, T. C.; MONTEIRO-VITORELLO, C. B.; CRESTE, S.; BOSCARIOL-CAMARGO, R. L.; TAKITA, M. A.; CRISTOFANI-YALY, M.; SOUZA, A. A. de

Gene editing technologies have opened up the possibility of manipulating the genome of any organism in a predicted way. CRISPR technology is the most used genome editing tool and, in agriculture, it h... ...

Repository: BDPA     Publication year: 2023

Author(s): CAMARGO, L. S. de A.; PEREIRA, J. F.

The livestock performance in tropical regions has been limited by environmental conditions that causes heat stress and favors the development of parasites and diseases, impairing animal health. Heat s... ...

Repository: BDPA     Publication year: 2022

Author(s): SILVA JUNIOR, O. B. da; PESSOA FILHO, M. A. C. de P.; SA, M. E. L.; DEAL, R.; RAGOUSSIS, I.; GRATTAPAGLIA, D.; RECH FILHO, E. L.

ABSTRACT: Directional selection during crop domestication and advanced breeding has resulted in significant changes in plant genomes. The extent of intraspecific variation in a crop documents domestic... ...

Repository: BDPA     Publication year: 2018

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