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In this project we intend to reinforce a recent collaboration established between two French and Brazilian bioinformatics laboratories for the development of a structural genomics approach to function... ...

Repository: BDPA     Publication year: 2009

In order to improve binding affinity prediction, we developed a new scoring function, named STINGSF, derived from physical-chemical and structural features that describe the protein-ligand interaction... ...

Repository: BDPA     Publication year: 2015

We propose a new empirical scoring function for binding affinity prediction modeled based on physicochemical and structural descriptors that characterize the nano-environment that encompass both ligan... ...

Repository: BDPA     Publication year: 2016

ABSTRACT. Predicting enzyme class from protein structure parameters is a challenging problem in protein analysis. We developed a method to predict enzyme class that combines the strengths of statistic... ...

Repository: BDPA     Publication year: 2006

In this work, we present a method for predicting hot spot residues by using a set of structural and evolutionary parameters. Unlike previous studies, we use a set of parameters which do not depend on... ...

Repository: BDPA     Publication year: 2009

Diamond STING is a new version of the STING suite of programs for a comprehensive analysis of a relationship between protein sequence, structure, function and stability. We have added a number of new... ...

Repository: BDPA     Publication year: 2005

The purpose of this work is to characterize PUFs to be used in GM crops pipelines using orthology, co-expression networks and other tools. To date, we have downloaded, analyzed, and processed genomic... ...

Repository: BDPA     Publication year: 2019

RNA interference (RNAi)-mediated gene silencing can be used to control specific insect pest populations. Unfortunately, the variable efficiency in the knockdown levels of target genes has narrowed the... ...

Repository: BDPA     Publication year: 2021

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