Protein-protein interactions virtually regulate all processes inside cells, e.g. signal transduction, metabolic regulation, gene regulation, and immunological responses which occur in a specific way. Several experimental methods are capable of detecting interactions between proteins, which can range from cellular "resolution" to experiments which expose atom level interactions. However, the performance of these combined experiments which generate complete information regarding the network of pro ...

Status: Completed     Start date: Sat Aug 01 00:00:00 GMT-03:00 2009

Enzymes have their function essentially determined by specific residue known as catalytic residue. Most methods to predict enzyme catalytic residue uses at least one criterion of primary sequence conservation. Considering that the function is a product of the structure, this project aims to identify among the structural descriptors available in the Sting software database those of higher relevance in the discrimination of catalytic residue. Thus, the project will propose a new enzyme classificat

Status: Completed     Start date: Sun Aug 01 00:00:00 GMT-03:00 2010