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Author(s): PRADO, G. S.; PINHEIRO, T. T.; FARIA, J. C. de; VIANELLO, R. P.

Introdução. Mecanismos de reparo genético. Non-homologous end joining (NHEJ). Mecanismo bioquímico. Edição de Genomas via NHEJ - aplicações práticas. Modulação e otimização de promotores. Ribonucleopr... ...

Repository: BDPA     Publication year: 2020

Author(s): PRADO, G. S.; PINHEIRO, T. T.; FARIA, J. C. de; VIANELLO, R. P.

We will focus here on the use of the CRISPR/Cas system to induce mutations via NHEJ. The NHEJ mechanism acts in most of the cell cycle and is not based on homology to repair DNA, causing mutations suc... ...

Repository: BDPA     Publication year: 2021

Author(s): MOLINARI, H. B. C.; VIEIRA, L. R.; SILVA, N. V. e; PRADO, G. S.; LOPES FILHO, J. F.

Chapter 1: Introduction to genome editing in plants. Chapter 2: Genome editing via non-homologous end-joining (NHEJ) and ribonucleoproteins (RNP). Chapter 3: Genome editing by CRISPR/Cas via homologou... ...

Repository: BDPA     Publication year: 2021

Author(s): MOLINARI, H. B. C.; VIEIRA, L. R.; SILVA, N. V. e; PRADO, G. S.; LOPES FILHO, J. H.

Capítulo 1: Introdução à edição genômica em plantas; Capítulo 2: Edição de genoma via non-homologous end joining (NHEJ) e ribonucleoproteínas (RNP); Capítulo 3: Edição de genoma por CRISPR/Casvia reco... ...

Repository: BDPA     Publication year: 2020

Author(s): VANEGAS K. G.; RENDSVIG, J. K. H.; JARCZYSKA, Z. D.; CÔRTES, M. V. de C. B.; VAN ESCH, A. P.; MORERA-GÓMEZ, M.; CONTESINI, F. J.; MORTENSEN, U. H.

The introduction of CRISPR technologies has revolutionized strain engineering in filamentous fungi. However, its use in commercial applications has been hampered by concerns over intellectual property... ...

Repository: BDPA     Publication year: 2023

Author(s): VIEIRA, L. R.; FREITAS, N. C.; JUSTEN, F.; MIRANDA, V. de J.; GARCIA, B. de O.; NEPOMUCENO, A. L.; FUGANTI-PAGLIARINI, R.; FELIPE, M. S. S.; MOLINARI, H. B. C.; VELINI, E. D.; PINTO, E. R. de C.; DAGLI, M. L. Z.; ANDRADE, G.; FERNANDES, P. M. B.; MERTZ-HENNING, L. M.; KOBAYASHI, A. K.

The regulation of the use of products obtained through genome-editing techniques has been the subject of great debate worldwide. Currently, the discussions are mainly focused on whether products obtai... ...

Repository: BDPA     Publication year: 2021

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